June 15, 2021

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CollPlant Announces Advancement and Worldwide Commercialization Settlement with Allergan Aesthetics, an AbbVie enterprise, for

Probable to get up to $103 million in upfront and milestone payments, in addition to royalties and other payments

REHOVOT, Israel, Feb. 8, 2021 /PRNewswire/ — CollPlant Biotechnologies right now announced it has entered into a all over the world special growth and commercialization agreement for dermal and tender tissue filler items with Allergan Aesthetics, an AbbVie enterprise.

https://mma.prnewswire.com/media/1434316/Dermal_Filler.jpg [https://mma.prnewswire.com/media/1434316/Dermal_Filler.jpg]

CollPlant has granted Allergan Aesthetics globally exclusivity to use its plant-derived recombinant human collagen (rhCollagen) in blend with Allergan Aesthetics’ proprietary technologies, for the production and commercialization of dermal and gentle tissue fillers. In addition, Allergan Aesthetics has the right of initial negotiation for CollPlant’s technological innovation in two potential added products.

CollPlant will get an upfront payment of $14 million and is entitled to obtain up to an further $89 million in milestone payments. In addition, CollPlant is eligible to acquire royalty payments and a fee for the manufacture and source of rhCollagen to Allergan Aesthetics.

Yehiel Tal, Chief Govt Officer of CollPlant, mentioned, “We are extremely happy to formalize this collaboration with Allergan Aesthetics, the globally leader in dermal and gentle tissue fillers. We feel that combining systems from Allergan Aesthetics and CollPlant will make a paradigm shift in the healthcare aesthetics field. CollPlant’s rhCollagen is non-immunogenic and non-allergenic, and offers greater tissue regeneration general performance above animal-derived collagen which is at present employed in healthcare aesthetics. This settlement even further validates CollPlant’s technological know-how as the gold standard collagen for regenerative and aesthetic medicine. We glimpse ahead to a highly effective partnership.”

Roger J. Pomerantz, MD, FACP, Chairman of the Board of Administrators at CollPlant, claimed, “Our enterprise is particularly energized to extend our perform in clinical aesthetics towards commercialization in the dermal filler sector, which is projected to get to $10 billion by 2026. This collaboration is a key action forward, firmly positioning CollPlant at the following amount in making use of our regenerative medicine technology to deal with new parts in biomedicine.”

About CollPlant

CollPlant is a regenerative and aesthetic drugs organization focused on 3D bioprinting of tissues and organs, and health care aesthetics. CollPlant’s products and solutions are dependent on its rhCollagen (recombinant human collagen) that is developed with CollPlant’s proprietary plant primarily based genetic engineering technology.

CollPlant’s items tackle indications for the assorted fields of tissue maintenance, aesthetics and organ manufacturing, and are ushering in a new period in regenerative and aesthetic drugs.

CollPlant’s flagship rhCollagen BioInk item line is suitable for 3D bioprinting of tissues and organs. In 2018, CollPlant entered into a licensing agreement with United Therapeutics, whereby United Therapeutics is utilizing CollPlant’s BioInks in the manufacture of 3D bioprinted lungs for transplant in human beings.

For far more information and facts, go to http://www.collplant.com [http://www.collplant.com/].

Contacts at CollPlant:

Eran RotemDeputy CEO & Chief Fiscal OfficerTel: + 972-73-2325600/631E mail: [email protected][mailto:[email protected]]

Secure Harbor for Ahead-Seeking Statements

This press launch may possibly contain ahead-on the lookout statements. Forward-searching statements could involve, but are not limited to, statements relating to CollPlant’s targets, plans and approaches, as very well as statements, other than historic info, that tackle actions, events or developments that CollPlant intends, expects, jobs, believes or anticipates will or may perhaps come about in the foreseeable future. These statements are often characterised by terminology these types of as “thinks,” “hopes,” “could,” “anticipates,” “really should,” “intends,” “programs,” “will,” “expects,” “estimates,” “initiatives,” “positioned,” “method” and equivalent expressions and are primarily based on assumptions and assessments designed in light-weight of management’s practical experience and perception of historical traits, present-day problems, predicted long term developments and other aspects thought to be acceptable. Forward-wanting statements are not guarantees of foreseeable future efficiency and are matter to challenges and uncertainties that could result in precise effects to vary materially from these expressed or implied in this sort of statements. Quite a few aspects could result in CollPlant’s precise routines or success to vary materially from the routines and results anticipated in forward-seeking statements, like, but not minimal to, the pursuing: CollPlant’s history of sizeable losses and its need to elevate additional cash and its incapability to get hold of more cash on suitable terms, or at all CollPlant’s anticipations regarding the timing and price tag of commencing medical trials with respect to goods which are dependent on CollPlant’s rhCollagen CollPlant’s capacity to get favorable pre-clinical and medical trial final results regulatory action with respect to the products, including but not minimal to acceptance of an application for internet marketing authorization, evaluation and approval of these kinds of software, and, if accepted, the scope of the authorised indication and labeling commercial accomplishment and marketplace acceptance of the goods CollPlant’s means to build sales and marketing and advertising abilities or enter into agreements with third events and its reliance on 3rd-occasion distributors and resellers CollPlant’s capability to set up and retain strategic partnerships and other company collaborations CollPlant’s reliance on third parties to carry out some factors of its product producing the scope of defense CollPlant is equipped to set up and retain for mental property rights and the companies’ means to run their company devoid of infringing the intellectual property rights of many others the total world-wide financial atmosphere the impression of competitiveness and new technologies standard marketplace, political, and economic situations in the nations around the world in which the companies operate projected capital expenditures and liquidity improvements in the companies’ tactic and litigation and regulatory proceedings. Far more thorough data about the threats and uncertainties impacting CollPlant is contained underneath the heading “Possibility Elements” integrated in CollPlant’s most the latest yearly report on Sort 20-F, respectively, filed with the SEC, and in other filings that CollPlant has designed and could make with the SEC in the long term. The ahead-searching statements contained in this press release are made as of the date of this press launch and replicate CollPlant’s recent sights with regard to future gatherings, and neither company undertakes, and each enterprise particularly disclaims, any obligation to update or revise any ahead-wanting statements, no matter whether as a consequence of new facts, future events or in any other case.

Image — https://mma.prnewswire.com/media/1434316/Dermal_Filler.jpg [https://mma.prnewswire.com/media/1434316/Dermal_Filler.jpg]

World wide web web site: http://www.collplant.com//